Bankpeptide Biotinylated Peptides
In biochemistry, biotinylation is the process of covalently attaching biotin to a protein, nucleic acid or other molecule. Biotinylation is rapid, specific and is unlikely to disturb the natural function of the molecule due to the small size of biotin (MW = 244.31 g/mol). Biotin binds to streptavidin and avidin with an extremely high affinity, fast on-rate, and high specificity, and these interactions are exploited in many areas of biotechnology to isolate biotinylated molecules of interest. Biotin-binding to streptavidin and avidin is resistant to extremes of heat, pH and proteolysis, making capture of biotinylated molecules possible in a wide variety of environments. Also, multiple biotin molecules can be conjugated to a protein of interest, which allows binding of multiple streptavidin, avidin or neutravidin protein molecules and increases the sensitivity of detection of the protein of interest. There is a large number of biotinylation reagents available that exploit the wide range of possible labelling methods.
Bankpeptide routinely synthesizes biotinylated peptides for use in protein-protein interaction studies. We provide:
Biotin can be separated from the peptide by a variety of different linkers or spacers. Nevertheless, it is recommended that a flexible spacer such as Ahx (a 6-carbon linker) is included to render the biotin label more stable or flexible.
Documentation and Packaging
Each peptide is shipped with a Document of HPLC and MS data for free. Other test datas can also be provided according to customer demand . Peptides are packed with ice bag and desiccants during shipment and storage. After opening, we recommend peptides are stored dry in a freezer (details given in our technical guide to handling peptides; a copy is shipped with each peptide).

a.What is the minimum quantity for a peptide?

The minimun for one peptide should be 1mg, and there is no maximum quantity for a peptide at Bankpeptide.

b.Which kind of solvent should I use?

According to your needs, the peptides can often dissolved in water, DMF,DMSO, and PBS Buffer.

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Ordering & Contact Information
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Reference:A new orally available glucagon-like peptide-1 receptor agonist,

biotinylated exendin-4, displays improved hypoglycemic effects in db/db mice.Cheng-Hao Jin,

Su Young Chae, Sohee Son

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